Concepedia

Oral administration of pulverized Konjac glucomannan prevents the increase of plasma immunoglobulin E and immunoglobulin G levels induced by the injection of syngeneic keratinocyte extracts in BALB/c mice

Souichi Oomizu, Nobukazu Onishi, Hidenori Suzuki, K. Ueda, Mitsuru Mochizuki, Kenichi Morimoto, Seiji Kawamoto, Koichiro Ono, Yoshikazu Kameyoshi, Michihiro Hide

Clinical & Experimental Allergy · 2005 · 41 citations · 27 references

DOI

Abstract

These results suggested that oral administration of PKGM prevents the elevation of plasma IgE by suppressing IgE class switching in B cells and/or the commitment development of naive lymphocytes to both T-helper type 1 (Th1) and Th2.

References

27

Real time quantitative PCR.

Chris Heid, Junko Stevens, Kenneth J. Livak et al. · Genome Research · 1996 · 6.2K citations · Full text

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A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Susanne J. Szabo, Sean Kim, Gina L. Costa et al. · Cell · 2000 · 3.5K citations · Full text

, , +5

Natural adjuvants: Endogenous activators of dendritic cells

Stefania Gallucci, Martijn P. Lolkema, Polly Matzinger · Nature Medicine · 1999 · 1.6K citations

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Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

Juha Punnonen, Gregorio Aversa, Benjamin G. Cocks et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations

, , +19

A Critical Role for IL-21 in Regulating Immunoglobulin Production

Katsutoshi Ozaki, Rosanne Spolski, Carl G. Feng et al. · Science · 2002 · 956 citations

, , +14