Concepedia

Natural adjuvants: Endogenous activators of dendritic cells

Stefania Gallucci, Martijn P. Lolkema, Polly Matzinger

Nature Medicine · 1999 · 1.6K citations · 37 references

DOI

Concepts

References

37

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Federica Sallusto, Antonio Lanzavecchia · The Journal of Experimental Medicine · 1994 · 5.2K citations · Full text

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Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

Kensuke Inaba, Muneo Inaba, Nikolaus Romani et al. · The Journal of Experimental Medicine · 1992 · 3.8K citations · Full text

, , +12

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

Valerie A. Fadok, Donna L. Bratton, Anatole Konowal et al. · Journal of Clinical Investigation · 1998 · 3.1K citations · Full text

, , +17

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

Federica Sallusto, Marina Cella, Carlo Danieli et al. · The Journal of Experimental Medicine · 1995 · 2.5K citations · Full text

, , +17

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

Matthew L. Albert, Birthe Sauter, Nina Bhardwaj · Nature · 1998 · 2.3K citations

, , +16