Concepedia

Keratinocyte Activation

Keratinocyte Activation is a biological response process in which epidermal keratinocytes, upon exposure to chemical allergens, upregulate the expression of co-stimulatory molecules and pro-inflammatory cytokines, thereby initiating the cutaneous immune cascade characteristic of skin sensitization.

4.4K

Publications

258.9K

Citations

18.2K

Authors

2.9K

Institutions

Publications per year

2017–2026

859

Parents

Publications

4.4K

Cytokine modulation of atopic dermatitis filaggrin skin expression

Michael Howell, Byung Eui Kim, Peisong Gao et al. · Journal of Allergy and Clinical Immunology · 2007 · 1.1K citations · Full text

, , +14

Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes

James G. Rheinwald, Howard Green · Nature · 1977 · 1.1K citations

, , +11

Decreased Level of Ceramides in Stratum Corneum of Atopic Dermatitis: An Etiologic Factor in Atopic Dry Skin?

Genji Imokawa, Akihito Abe, Kumi Jin et al. · Journal of Investigative Dermatology · 1991 · 1K citations

, , +16

Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis

Julia Gittler, Avner Shemer, Mayte Suárez‐Fariñas et al. · Journal of Allergy and Clinical Immunology · 2012 · 958 citations · Full text

, , +17

Production and auto-induction of transforming growth factor-α in human keratinocytes

Robert J. Coffey, Rik Derynck, Josiah N. Wilcox et al. · Nature · 1987 · 863 citations

, , +10

1–5 of 4.4K

Authors

18.2K

  1. JJ
    John J. Voorhees

    University of Michigan, United States

    28 publications · 2.1K citations

    25

    h-index

  2. HO
    Hideoki Ogawa

    Juntendo University, Japan

    29 publications · 2.1K citations

    23

    h-index

  3. BJ
    Brian J. Nickoloff

    Loyola University Medical Center, United States

    29 publications · 2.8K citations

    23

    h-index

  4. MF
    Masutaka Furue

    Kyushu University, Japan

    28 publications · 1.9K citations

    22

    h-index

  5. SW
    Shinichi Watanabe

    Teikyo University, Japan

    26 publications · 1.4K citations

    22

    h-index

1–5 of 18.2K

Institutions

2.9K

  1. University of Michigan

    Ann Arbor, United States

    51 h-index

    410 publications

    35.3K citations

  2. Inserm

    Paris, France

    49 h-index

    498 publications

    38.4K citations

  3. National Cancer Institute

    Bethesda, United States

    42 h-index

    168 publications

    18.6K citations

  4. Heidelberg University

    Heidelberg, Germany

    39 h-index

    209 publications

    13.2K citations

  5. University of California, San Francisco

    San Francisco, United States

    37 h-index

    176 publications

    20K citations

  6. National Institutes of Health

    Bethesda, United States

    34 h-index

    135 publications

    13.8K citations

  7. German Cancer Research Center

    Heidelberg, Germany

    33 h-index

    128 publications

    8.5K citations

  8. University of Colorado Denver

    Denver, United States

    32 h-index

    163 publications

    16.4K citations

1–8 of 2.9K

Venues

  1. Journal of Investigative Dermatology

    JID · 757 publications · 55.5K citations

    116

    h-index

  2. The Journal of Immunology

    JI · 98 publications · 12.6K citations

    63

    h-index

  3. British Journal of Dermatology

    178 publications · 10.6K citations

    55

    h-index

  4. Journal of Biological Chemistry

    JBC · 91 publications · 7.8K citations

    53

    h-index

  5. PubMed

    Repository · 146 publications · 7.9K citations

    52

    h-index

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