Brian J. Nickoloff

Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis

Kenneth B. Gordon, Andrew Blauvelt, Kim Papp et al. · New England Journal of Medicine · 2016 · 818 citations · Full text

Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials

C.E.M. Griffiths, Kristian Reich, Mark Lebwohl et al. · The Lancet · 2015 · 815 citations

Randomised Trials, Clinical Trials, Clinical Dermatology +5

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

Shigetoshi Sano, Keith Syson Chan, Steve Carbajal et al. · Nature Medicine · 2004 · 739 citations

Inflammation, Skin Development, Medicine +10

Spontaneous Development of Psoriasis in a New Animal Model Shows an Essential Role for Resident T Cells and Tumor Necrosis Factor-α

Onur Boyman, Hans Peter Hefti, Curdin Conrad et al. · The Journal of Experimental Medicine · 2004 · 508 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +23

Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin

Brian J. Nickoloff, Yathi M. Naidu · Journal of the American Academy of Dermatology · 1994 · 459 citations

Inflammation, Signal Transduction, Cutaneous Biology +11