Concepedia

Allosteric Regulation of Protein Kinase PKCζ by the N-Terminal C1 Domain and Small Compounds to the PIF-Pocket

Laura A. Lopez-Garcia, Jörg O. Schulze, Wolfgang Fröhner, Hua Zhang, Evelyn Süß, Nadja Weber, Jeanette Navratil, Sabine Amon, Valérie Hindie, Stefan Zeuzem,

Chemistry & Biology · 2011 · 65 citations · 31 references

DOI

Concepts

References

31

Protein Kinase C Contains a Pseudosubstrate Prototope in Its Regulatory Domain

Colin M. House, Bruce E. Kemp · Science · 1987 · 1K citations

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Crystal structure of an activated Akt/Protein Kinase B ternary complex with GSK3-peptide and AMP-PNP

Jing Yang, Peter Cron, Valerie M. Good et al. · Nature Structural Biology · 2002 · 504 citations

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PKC zeta is a molecular switch in signal transduction of TNF‐alpha, bifunctionally regulated by ceramide and arachidonic acid.

Gerhard Müller, Mohammed Akli Ayoub, Peter Störz et al. · The EMBO Journal · 1995 · 501 citations · Full text

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Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation

Jing Yang, Peter Cron, Vivienne Thompson et al. · Molecular Cell · 2002 · 418 citations · Full text

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Taxonomy and function of C1 protein kinase C homology domains

James H. Hurley, Alexandra C. Newton, Peter J. Parker et al. · Protein Science · 1997 · 364 citations · Full text

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