Concepedia

IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells

Claire M. Perks, Ellen G Vernon, AH Rosendahl, David W. Tonge, J.M.P. Holly

Oncogene · 2007 · 167 citations · 30 references

DOI

Concepts

References

30

Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

Vuk Stambolic, Akira Suzuki, José Luís de la Pompa et al. · Cell · 1998 · 2.6K citations · Full text

, , +16

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Zhenbang Chen, Lloyd C. Trotman, David R. Shaffer et al. · Nature · 2005 · 2K citations · Full text

, , +16

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients

Yoichi Nagata, Keng‐Hsueh Lan, Xiaoyan Zhou et al. · Cancer Cell · 2004 · 1.9K citations · Full text

, , +14

Regulation of PTEN Transcription by p53

Vuk Stambolic, David MacPherson, D. Sas et al. · Molecular Cell · 2001 · 915 citations · Full text

, , +12

Pten Dose Dictates Cancer Progression in the Prostate

Lloyd C. Trotman, Masaru Niki, Zohar Dotan et al. · PLoS Biology · 2003 · 668 citations · Full text

, , +15