Yoichi Nagata

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients

Yoichi Nagata, Keng‐Hsueh Lan, Xiaoyan Zhou et al. · Cancer Cell · 2004 · 1.8K citations · Full text

Trastuzumab Resistance, Pten Activation Contributes, Medicine +12

Phosphorylation on Tyrosine-15 of p34Cdc2 by ErbB2 Inhibits p34Cdc2 Activation and Is Involved in Resistance to Taxol-Induced Apoptosis

Ming Tan, Jing Tong, Keng‐Hsueh Lan et al. · Molecular Cell · 2002 · 129 citations · Full text

Signal Transduction, Biochemistry, Taxol-induced Apoptosis +12

Combined trastuzumab and paclitaxel treatment better inhibits ErbB‐2‐mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone

Kristine S. Klos, Xiaoyan Zhou, Sangkyou Lee et al. · Cancer · 2003 · 110 citations · Full text

ErbB2 Promotes Src Synthesis and Stability: Novel Mechanisms of Src Activation That Confer Breast Cancer Metastasis

Ming Tan, Ping Li, Kristine S. Klos et al. · Cancer Research · 2005 · 106 citations · Full text

Tumor Biology, Radiation Oncology, Src Kinase +15

The stabilization mechanism of mutant-type p53 by impaired ubiquitination: the loss of wild-type p53 function and the hsp90 association

Yoichi Nagata, Tadashi Anan, Tetsuo Yoshida et al. · Oncogene · 1999 · 100 citations

Genome Instability, Cell Regulation, Molecular Regulation +9