Kristine S. Klos

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients

Yoichi Nagata, Keng‐Hsueh Lan, Xiaoyan Zhou et al. · Cancer Cell · 2004 · 1.9K citations · Full text

Medicine, Cancer Biology, Oncology +14

Activation of the Akt/Mammalian Target of Rapamycin/4E-BP1 Pathway by ErbB2 Overexpression Predicts Tumor Progression in Breast Cancers

Xiaoyan Zhou, Ming Tan, Valerie Stone Hawthorne et al. · Clinical Cancer Research · 2004 · 312 citations · Full text

Medicine, Cancer Biology, Oncology +17

ErbB2 Increases Vascular Endothelial Growth Factor Protein Synthesis via Activation of Mammalian Target of Rapamycin/p70S6K Leading to Increased Angiogenesis and Spontaneous Metastasis of Human Breast Cancer Cells

Kristine S. Klos, Shannon L. Wyszomierski, Menghong Sun et al. · Cancer Research · 2006 · 200 citations · Full text

Medicine, Cancer Biology, Oncology +17

Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-β1 in human breast cancer cells

Jun Yao, Shunbin Xiong, Kristine S. Klos et al. · Oncogene · 2001 · 170 citations

Life Sciences, Cell Biology, Molecular Biology +11

The Wnt Receptor, Lrp5, Is Expressed by Mouse Mammary Stem Cells and Is Required to Maintain the Basal Lineage

Nisha M. Badders, Shruti Goel, Rod J. Clark et al. · PLoS ONE · 2009 · 129 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +17