Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-β1 in human breast cancer cells

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

Thiennu H. Vu, J. Michael Shipley, Gabriele Bergers et al. · Cell · 1998 · 1.8K citations · Full text

Life Sciences, Cell Biology, Pathology +11

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis

Qin Yu, Ivan Stamenkovic · Genes & Development · 2000 · 1.7K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Identification of Heregulin, a Specific Activator of p185 ^erbB2

William E. Holmes, Mark X. Sliwkowski, Robert W. Akita et al. · Science · 1992 · 965 citations

Medicine, Molecular Biology, Oncology +14

Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family.

Gregory D. Plowman, Jean‐Michel Culouscou, Gena S. Whitney et al. · Proceedings of the National Academy of Sciences · 1993 · 718 citations

Life Sciences, Molecular Biology, Oncology +14

Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin.

Mark X. Sliwkowski, Gabriele Schaefer, Robert W. Akita et al. · Journal of Biological Chemistry · 1994 · 644 citations · Full text

Life Sciences, Molecular Biology, Oncology +13