Concepedia

Gelatinase Activity

Gelatinase Activity is a biochemical assay that quantifies the enzymatic capacity of matrix metalloproteinases, particularly MMP-2 and MMP-9, to degrade gelatin substrates, thereby serving as a functional marker of extracellular matrix remodeling in connective tissue breakdown.

3.5K

Publications

277.6K

Citations

14K

Authors

2.6K

Institutions

Publications per year

2017–2026

209

Variants

Gelatinolytic Activity

Parents

Publications

3.5K

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

Zorina S. Galis, Galina K. Sukhova, Michael W. Lark et al. · Journal of Clinical Investigation · 1994 · 2.5K citations · Full text

, , +16

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

Thiennu H. Vu, J. Michael Shipley, Gabriele Bergers et al. · Cell · 1998 · 1.8K citations · Full text

, , +11

Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase

Lars Kjeldsen, Anni Johnsen, Henrik Sengeløv et al. · Journal of Biological Chemistry · 1993 · 1.3K citations · Full text

, , +17

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability.

Sanjay Rajagopalan, Santhini Ramasamy, David G. Harrison et al. · Journal of Clinical Investigation · 1996 · 1.1K citations · Full text

, , +13

Matrix Metalloproteinase-Mediated Disruption of Tight Junction Proteins in Cerebral Vessels is Reversed by Synthetic Matrix Metalloproteinase Inhibitor in Focal Ischemia in Rat

Yi Yang, Eduardo Y. Estrada, Jeffrey F. Thompson et al. · Journal of Cerebral Blood Flow & Metabolism · 2006 · 1.1K citations

, , +17

1–5 of 3.5K

Authors

14K

  1. GO
    Ghislain Opdenakker

    Rega Institute for Medical Research, Belgium

    92 publications · 7.3K citations

    45

    h-index

  2. GM
    Gillian Murphy

    University of East Anglia, United Kingdom

    46 publications · 8.7K citations

    40

    h-index

  3. WG
    William G. Stetler‐Stevenson

    National Cancer Institute, United States

    47 publications · 7.1K citations

    38

    h-index

  4. YO
    Yasunori Okada

    Keio University, Japan

    44 publications · 7.1K citations

    37

    h-index

  5. MS
    Motoharu Seiki

    The University of Tokyo, Japan

    41 publications · 5.9K citations

    35

    h-index

1–5 of 14K

Institutions

2.6K

  1. Inserm

    Paris, France

    49 h-index

    346 publications

    27.8K citations

  2. University of California, San Francisco

    San Francisco, United States

    48 h-index

    203 publications

    41.8K citations

  3. KU Leuven

    Leuven, Belgium

    48 h-index

    443 publications

    35.6K citations

  4. University of Helsinki

    Helsinki, Finland

    47 h-index

    261 publications

    27.2K citations

  5. Kanazawa University

    Kanazawa, Japan

    46 h-index

    195 publications

    28.4K citations

  6. Rega Institute for Medical Research

    Leuven, Belgium

    43 h-index

    355 publications

    32.9K citations

  7. Harvard University

    Cambridge, United States

    38 h-index

    143 publications

    25.5K citations

  8. National Institutes of Health

    Bethesda, United States

    38 h-index

    190 publications

    24.9K citations

1–8 of 2.6K

Venues

  1. Journal of Biological Chemistry

    JBC · 172 publications · 27.9K citations

    97

    h-index

  2. PubMed

    Repository · 297 publications · 24.2K citations

    91

    h-index

  3. International Journal of Cancer

    67 publications · 5.3K citations

    43

    h-index

  4. Biochemical Journal

    BJ · 55 publications · 6.6K citations

    41

    h-index

  5. Journal of Clinical Investigation

    JCI · 30 publications · 10K citations

    30

    h-index

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