Publication | Open Access

Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein–protein interaction through structure-based drug design

Hdm2-p53 Protein–protein InteractionDrug TargetMedicineRational Drug DesignStructure-based Drug DesignPharmacotherapyPharmacodynamic ModelingPharmacology1,4-Benzodiazepine-2,5-dione AntagonistsBiomolecular Engineering