Cooperative transformation of 32D cells by the combined expression of IRS-1 and V-Ha-Ras

Antiapoptotic Signalling by the Insulin-Like Growth Factor I Receptor, Phosphatidylinositol 3-Kinase, and Akt

George Kulik, Anke Klippel, Michael J. Weber · Molecular and Cellular Biology · 1997 · 1.1K citations · Full text

Life Sciences, Cell Biology, Apoptosis +16

Matrix adhesion and Ras transformation both activate a phosphoinositide 3‐OH kinase and protein kinase B/Akt cellular survival pathway

Asim Khwaja, Pablo Rodriguez‐Viciana, Stefan Wennström et al. · The EMBO Journal · 1997 · 1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

The IRS-signalling system: A network of docking proteins that mediate insulin action

Morris F. White · Molecular and Cellular Biochemistry · 1998 · 533 citations

Life Sciences, Biochemistry, Molecular Biology +14

Multiple Signaling Pathways of the Insulin-Like Growth Factor 1 Receptor in Protection from Apoptosis

Francesca Peruzzi, Marco di Prisco, Michael Dews et al. · Molecular and Cellular Biology · 1999 · 501 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

The IGF-I receptor in cell growth, transformation and apoptosis

Renato Baserga, Atsushi Hongo, Michele Rubini et al. · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 1997 · 441 citations

Life Sciences, Cell Biology, Molecular Biology +14