Concepedia

Hepatic cytochrome P-4503A (CYP3A) activity in the elderly

Christine M. Hunt, William R. Westerkam, Gregg M. Stave, Joanne A. P. Wilson

Mechanisms of Ageing and Development · 1992 · 89 citations · 30 references

DOI

Concepts

References

30

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.

F. Peter Guengerich, M V Martin, Philippe Beaune et al. · Journal of Biological Chemistry · 1986 · 730 citations · Full text

, , +17

Cyclosporine metabolism in human liver: Identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs

Thomas Kronbach, Volker Fischer, Urs Meyer · Clinical Pharmacology & Therapeutics · 1988 · 539 citations

, , +17

Cytochrome P-450 hPCN3, a Novel Cytochrome P-450 IIIA Gene Product That Is Differentially Expressed in Adult Human Liver

Toshifumi Aoyama, Saki Yamano, David J. Waxman et al. · Journal of Biological Chemistry · 1989 · 482 citations · Full text

, , +12

Human liver microsomal steroid metabolism: Identification of the major microsomal steroid hormone 6β-hydroxylase cytochrome P-450 enzyme

David J. Waxman, C Attisano, F. Peter Guengerich et al. · Archives of Biochemistry and Biophysics · 1988 · 415 citations

, , +11

Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients.

Paul B. Watkins, Scott A Murray, L G Winkelman et al. · Journal of Clinical Investigation · 1989 · 351 citations · Full text

, , +15