Aromatic isosteres as conformational probes for an isoprenyl subunit: application to inhibitors of squalene synthase

Optimization of parameters for semiempirical methods I. Method

James J. P. Stewart · Journal of Computational Chemistry · 1989 · 7.6K citations

Natural Sciences, Materials Science, Computational Mechanics +4

Palladium- or nickel-catalyzed cross coupling. A new selective method for carbon-carbon bond formation

Ei‐ichi Negishi · Accounts of Chemical Research · 1982 · 1.1K citations

Natural Sciences, Chemistry, Catalysis +13

The facile dealkylation of phosphonic acid dialkyl esters by bromotrimethylsilane

Charles E. McKenna, Melvin T. Higa, Neil H. Cheung et al. · Tetrahedron Letters · 1977 · 445 citations

Natural Sciences, Chemistry, Organic Chemistry +5

Nickel- or palladium-catalyzed cross coupling. 31. Palladium- or nickel-catalyzed reactions of alkenylmetals with unsaturated organic halides as a selective route to arylated alkenes and conjugated dienes: scope, limitations, and mechanism

Ei‐ichi Negishi, Tamotsu Takahashi, Shigeru Baba et al. · Journal of the American Chemical Society · 1987 · 298 citations

Natural Sciences, Chemistry, Catalysis +13

Controlled carbometalation. 20. Carbometalation reaction of alkynes with organoalene-zirconocene derivatives as a route to stereo-and regiodefined trisubstituted alkenes

Ei‐ichi Negishi, David E. Van Horn, Tadao Yoshida · Journal of the American Chemical Society · 1985 · 246 citations

Natural Sciences, Chemistry, Catalysis +6