Carl P. Ciosek

An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells.

H Jamil, David A. Gordon, David C. Eustice et al. · Proceedings of the National Academy of Sciences · 1996 · 148 citations · Full text

Transfer Protein, Lipid Movement, Cellular Physiology +17

Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo.

Carl P. Ciosek, David R. Magnin, Thomas Harrity et al. · Journal of Biological Chemistry · 1993 · 102 citations · Full text

Pharmaceutical Science, Lipophilic 1,1-Bisphosphonates, Pharmacotherapy +16

Isoprenoid (phosphinylmethyl)phosphonates as inhibitors of squalene synthetase

Scott A. Biller, Cornelia J. Forster, Eric M. Gordon et al. · Journal of Medicinal Chemistry · 1988 · 85 citations · Full text

Pharmaceutical Science, Altmetric Attention Score, Squalene Synthetase +20

Human synoviocytes: activation and desensitization by prostaglandins and 1-epinephrine.

David S. Newcombe, Carl P. Ciosek, Yoshinori Ishikawa et al. · Proceedings of the National Academy of Sciences · 1975 · 79 citations · Full text

Receptor Site, Immunology, Cellular Physiology +17

The first potent inhibitor of squalene synthase: a profound contribution of an ether oxygen to inhibitor-enzyme interaction

Scott A. Biller, Michael J. Sofia, Barbara DeLange et al. · Journal of the American Chemical Society · 1991 · 76 citations

Pharmaceutical Science, Organic Chemistry, Chemical Biology +19