Pharmacokinetic–pharmacodynamic (PK–PD) modeling and the rational selection of dosage regimes for the prudent use of antimicrobial drugs

“VETERINARY PHARMACOLOGY AND THERAPEUTICS”

Australian Veterinary Journal · 1954 · 951 citations · Full text

Veterinary Behavioral Medicine, Animal Science, Medicine +3

Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas sepsis

George L. Drusano, Dachelle Johnson, Marc Rosen et al. · Antimicrobial Agents and Chemotherapy · 1993 · 421 citations

The use of Monte Carlo simulation to examine pharmacodynamic variance of drugs: fluoroquinolone pharmacodynamics against Streptococcus pneumoniae

Paul G. Ambrose, Dennis M. Grasela · Diagnostic Microbiology and Infectious Disease · 2000 · 117 citations

Streptococcus Pneumoniae, Pharmacodynamics, Medicine +10

Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs

Johan W. Mouton, Michael N. Dudley, Otto Cars et al. · International Journal of Antimicrobial Agents · 2002 · 103 citations

Bioequivalence, Medicine, Anti-infective Drugs +7

Antimicrobial breakpoints for Gram-negative aerobic bacteria based on pharmacokinetic–pharmacodynamic models with Monte Carlo simulation

Christopher R. Frei, Nathan P. Wiederhold, David S. Burgess · Journal of Antimicrobial Chemotherapy · 2008 · 102 citations · Full text