Concepedia

Model-based Drug Dosing

Model-Based Drug Dosing is a pharmacometric methodology that uses mathematical and statistical models derived from population pharmacokinetic-pharmacodynamic data to optimize individualized drug dosage regimens by predicting therapeutic outcomes and minimizing toxicity.

283

Publications

12.6K

Citations

1.4K

Authors

586

Institutions

Publications per year

2017–2026

119

Parents

Publications

283

Basic Concepts in Population Modeling, Simulation, and Model‐Based Drug Development—Part 2: Introduction to Pharmacokinetic Modeling Methods

DR Mould · CPT Pharmacometrics & Systems Pharmacology · 2013 · 880 citations · Full text

, , +17

Basic Concepts in Population Modeling, Simulation, and Model‐Based Drug Development

DR Mould · CPT Pharmacometrics & Systems Pharmacology · 2012 · 514 citations · Full text

, , +17

A Placebo- and Midazolam-Controlled Phase I Single Ascending-Dose Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of Remimazolam (CNS 7056)

Laurie J. Antonik, D. Ronald Goldwater, Gavin J. Kilpatrick et al. · Anesthesia & Analgesia · 2011 · 369 citations

, , +17

MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring

Johannes H. Proost, Dirk K. F. Meijer · Computers in Biology and Medicine · 1992 · 333 citations · Full text

, , +16

Comparison of Drug Dosing Recommendations Based on Measured GFR and Kidney Function Estimating Equations

Lesley A. Stevens, Thomas D. Nolin, Michelle M. Richardson et al. · American Journal of Kidney Diseases · 2009 · 262 citations

, , +11

1–5 of 283

Authors

1.4K

  1. RJ
    Ron J. Keizer

    Slotervaartziekenhuis, Netherlands

    9 publications · 427 citations

    9

    h-index

  2. MO
    Mats O. Karlsson

    Uppsala University, Sweden

    7 publications · 289 citations

    7

    h-index

  3. SG
    Sebastian G. Wicha

    Universität Hamburg, Germany

    7 publications · 355 citations

    7

    h-index

  4. MD
    Meindert Danhof

    Leiden University, Netherlands

    6 publications · 203 citations

    6

    h-index

  5. RT
    Rob ter Heine

    Radboud University Nijmegen, Netherlands

    6 publications · 243 citations

    6

    h-index

1–5 of 1.4K

Institutions

586

  1. Uppsala University

    Uppsala, Sweden

    13 h-index

    32 publications

    981 citations

  2. Radboud University Nijmegen

    Nijmegen, The Netherlands

    13 h-index

    65 publications

    1.6K citations

  3. Radboud University Medical Center

    Nijmegen, The Netherlands

    12 h-index

    64 publications

    1.5K citations

  4. Erasmus MC - Sophia Children’s Hospital

    Rotterdam, The Netherlands

    10 h-index

    20 publications

    704 citations

  5. Inserm

    Paris, France

    9 h-index

    16 publications

    392 citations

  6. University of Manchester

    Manchester, United Kingdom

    9 h-index

    12 publications

    428 citations

  7. Centre for Human Drug Research

    Leiden, The Netherlands

    9 h-index

    18 publications

    775 citations

  8. University of Florida

    Gainesville, United States

    8 h-index

    26 publications

    1K citations

1–8 of 586

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 16 publications · 806 citations

    16

    h-index

  2. Frontiers in Pharmacology

    13 publications · 423 citations

    13

    h-index

  3. Therapeutic Drug Monitoring

    12 publications · 689 citations

    12

    h-index

  4. CPT Pharmacometrics & Systems Pharmacology

    PSP · 10 publications · 1.7K citations

    10

    h-index

  5. Clinical Pharmacokinetics

    9 publications · 233 citations

    9

    h-index

1–5