Dirk K. F. Meijer

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Alex Sparreboom, Judith van Asperen, Ulrich Mayer et al. · Proceedings of the National Academy of Sciences · 1997 · 880 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Up–Regulation of the Multidrug Resistance Genes, Mrp1 And Mdr1b , and Down–Regulation of the Organic Anion Transporter, Mrp2, and the Bile Salt Transporter, Spgp, in Endotoxemic Rat Liver

Thera A. Vos, Guido Hooiveld, Hans Koning et al. · Hepatology · 1998 · 363 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring

Johannes H. Proost, Dirk K. F. Meijer · Computers in Biology and Medicine · 1992 · 333 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Substantial excretion of digoxin via the intestinal mucosa and prevention of long‐term digoxin accumulation in the brain by the mdrla P‐glycoprotein

Ulrich Mayer, Els Wagenaar, Jos H. Beijnen et al. · British Journal of Pharmacology · 1996 · 280 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Removal of Phosphate from Lipid A as a Strategy to Detoxify Lipopolysaccharide

Hafida Bentala, Willem R. Verweij, Ali Huizinga‐van der Vlag et al. · Shock · 2002 · 203 citations

Life Sciences, Biochemistry, Immunology +14