Marc Rosen

Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas sepsis

George L. Drusano, Dachelle Johnson, Marc Rosen et al. · Antimicrobial Agents and Chemotherapy · 1993 · 421 citations

Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation

W. Brian Dalton, Eric Helmenstine, Noel Walsh et al. · Journal of Clinical Investigation · 2019 · 68 citations · Full text

Genetics, Molecular Biology, Metabolic Remodeling +18

Design, Synthesis, and Evaluation of pH-Dependent Hydrolyzable Emetine Analogues as Treatment for Prostate Cancer

Emmanuel S. Akinboye, Marc Rosen, Samuel R. Denmeade et al. · Journal of Medicinal Chemistry · 2012 · 37 citations · Full text

N-2′ Position, Molecular Pharmacology, Medicinal Chemistry +13

Combining the pan‐aurora kinase inhibitor <scp>AMG</scp> 900 with histone deacetylase inhibitors enhances antitumor activity in prostate cancer

Channing J. Paller, Michel D. Wissing, Janet Mendonca et al. · Cancer Medicine · 2014 · 30 citations · Full text

Oncology, Antitumor Activity, Medicine +14

Anticancer activities of emetine prodrugs that are proteolytically activated by the prostate specific antigen (PSA) and evaluation of in vivo toxicity of emetine derivatives

Emmanuel S. Akinboye, Marc Rosen, Oladapo Bakare et al. · Bioorganic & Medicinal Chemistry · 2017 · 28 citations · Full text

Urology, Medicine, Prostate Specific Antigen +7