Selective inhibition of the interaction of C1q with immunoglobulins and the classical pathway of complement activation by steroids and triterpenoids sulfates

C-Reactive Protein and Complement Are Important Mediators of Tissue Damage in Acute Myocardial Infarction

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Life Sciences, Cardiology, Immunology +17

The Crystal Structure of the Globular Head of Complement Protein C1q Provides a Basis for Its Versatile Recognition Properties

Christine Gaboriaud, Arnaud Gruez, Monique Lacroix et al. · Journal of Biological Chemistry · 2003 · 360 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

<i>beta</i>-Amyloid activates complement by binding to a specific region of the collagen-like domain of the C1q A chain.

Hualiang Jiang, Debra Burdick, Charles Glabe et al. · The Journal of Immunology · 1994 · 336 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Complement in inflammatory tissue damage and disease

Tom Eirik Mollnes, Wen‐Chao Song, John D. Lambris · Trends in Immunology · 2002 · 165 citations

Life Sciences, Immunology, Pathology +12

β-Amyloid Fibrils Activate the C1 Complex of Complement Under Physiological Conditions: Evidence for a Binding Site for Aβ on the C1q Globular Regions

Pascale Tacnet‐Delorme, Sylvie Chevallier, Gérard J. Arlaud · The Journal of Immunology · 2001 · 152 citations · Full text

Life Sciences, Biochemistry, Immunology +15