Concepedia

<i>N</i>→<i>S</i> Acyl-Transfer-Mediated Synthesis of Peptide Thioesters Using Anilide Derivatives

Shugo Tsuda, Akira Shigenaga, Kiyomi Bando, Akira Otaka

Organic Letters · 2009 · 114 citations · 26 references

DOI

Concepts

Abstract

N-->S acyl-transfer-mediated synthesis of peptide thioesters utilizing an N-aminoacyl-N-sulfanylethylaminobenzoic acid derivative has been examined. The developed synthetic methodology for peptide thioesters is compatible with Fmoc solid-phase peptide synthesis (SPPS).

References

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