Concepedia

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

Takashi Shichita, Yuki Sugiyama, Hiroaki Ooboshi, Hiroshi Sugimori, Ryusuke Nakagawa, Ichiro Takada, Toru Iwaki, Yasunori Okada, Mitsuo Iida, Yoichiro Iwakura,

Nature Medicine · 2009 · 831 citations · 31 references

DOI

Concepts

References

31

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology · 2005 · 4.2K citations · Full text

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

Claire L. Langrish, Yi Chen, Wendy M. Blumenschein et al. · The Journal of Experimental Medicine · 2005 · 4K citations · Full text

, , +17

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

Jonathan Sherlock, Yi Chen, Craig A. Murphy et al. · Nature · 2003 · 2.9K citations

, , +14

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

Hania Kébir, Katharina Kreymborg, Igal Ifergan et al. · Nature Medicine · 2007 · 1.7K citations · Full text

, , +16

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

Christopher Lock, G Hermans, Rosetta Pedotti et al. · Nature Medicine · 2002 · 1.7K citations

, , +16