Pharmacokinetics difference of multiple active constituents from decoction and maceration of Fuzi Xiexin Tang after oral administration in rat by UPLC–MS/MS

Investigation of matrix effects in bioanalytical high‐performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery

Yunsheng Hsieh, Cymbylene Nardo, Xiao‐Ying Xu et al. · Rapid Communications in Mass Spectrometry · 2002 · 345 citations

Natural Sciences, Chemistry, Pharmaceutical Analysis +16

Extensive Intestinal First-Pass Elimination and Predominant Hepatic Distribution of Berberine Explain Its Low Plasma Levels in Rats

Yitong Liu, Haiping Hao, Hong‐Guang Xie et al. · Drug Metabolism and Disposition · 2010 · 339 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Absorption and enterohepatic circulation of baicalin in rats

Jie Xing, Dafang Zhong · Life Sciences · 2005 · 226 citations

Pharmacy, Pharmacokinetics, Pharmacology +10

Quantitative and chemical fingerprint analysis for quality control of Rhizoma Coptidischinensis based on UPLC-PAD combined with chemometrics methods

Weijun Kong, Yanling Zhao, Xiaohe Xiao et al. · Phytomedicine · 2009 · 158 citations

Agriculture, Food Science, Food Analysis +10

Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes

Yi Li, Gang Ren, Yanxiang Wang et al. · Journal of Translational Medicine · 2011 · 105 citations · Full text

Medicine, Biochemistry, Pharmacology +17