Journal of Natural Products · 2013 · 194 citations · 20 references
Life SciencesBotanyMedicinal ChemistryPlant BiochemistryPlant VirologyVirologyAntiviral AgentsAntiviral PharmacologyMedicinal Plant KnowledgeMedicinal PlantsPhenolic Compound AnalysisPlant VirusesAntiviral Natural ProductsAntiviral Structure-activity RelationshipsBioactive Plant CompoundsMedicinal HerbsPhenolic CompoundsPlant PhenolicsPlant-derived Natural ProductsTherapeutic Index Determination
Five new phenolic compounds, gramniphenols C-G (1-5), and eight known compounds (6-13) were isolated from the whole plant of Arundina gramnifolia. Compounds 1, 4, and 5 showed anti-tobacco mosaic virus activity, with IC(50) values of 20.8, 40.8, and 57.7 μM, respectively. Compounds 1-10 were also tested for their anti-HIV-1 activity; compounds 2, 3, and 6 displayed anti-HIV-1 activity with therapeutic index values above 100:1.
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Chemical constituents from Dendrobium densiflorum
Cheng‐Qi Fan, Wei Wang, Yiping Wang et al. · Phytochemistry · 2001 · 176 citations