Concepedia

Electrostatic effects on modification of charged groups in the active site cleft of subtilisin by protein engineering

Alan J. Russell, Paul Thomas, Alan R. Fersht

Journal of Molecular Biology · 1987 · 168 citations · 30 references

DOI

Concepts

References

30

An Algorithm for Least-Squares Estimation of Nonlinear Parameters

Donald W. Marquardt · Journal of the Society for Industrial and Applied Mathematics · 1963 · 30.4K citations

, , +11

Hydrogen bonding and biological specificity analysed by protein engineering

Alan R. Fersht, Jianping Shi, J.W. Knill-Jones et al. · Nature · 1985 · 1.1K citations

, , +16

Enzyme Structure and Mechanism

H. Gutfreund · FEBS Letters · 1978 · 760 citations · Full text

, , +13

Electrostatic Effects in Proteins

M. F. Perutz · Science · 1978 · 746 citations

, , +17

A sensitive new substrate for chymotrypsin

Eric G. Delmar, Corey Largman, James W. Brodrick et al. · Analytical Biochemistry · 1979 · 596 citations

, , +2