4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene and outcome of meningococcal disease

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

Anders Waage, P Brandtzæg, Alfred Halstensen et al. · The Journal of Experimental Medicine · 1989 · 1.2K citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +9

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.

Fletcher B. Taylor, Alvin Chang, CT Esmon et al. · Journal of Clinical Investigation · 1987 · 829 citations · Full text

Veterinary Medicine, Biochemistry, Pharmacology +17

The two allele sequences of a common polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene respond differently to interleukin-1 in HepG2 cells

Sally J. Dawson, B. Wiman, Anders Hamsten et al. · Journal of Biological Chemistry · 1993 · 569 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Plasma Endotoxin as a Predictor of Multiple Organ Failure and Death in Systemic Meningococcal Disease

P Brandtzæg, Peter Kierulf, Peter Gaustad et al. · The Journal of Infectious Diseases · 1989 · 560 citations

Veterinary Medicine, Immunology, Infectious Diseases +17

Promotion and Subsequent Inhibition of Plasminogen Activation after Administration of Intravenous Endotoxin to Normal Subjects

Anthony F. Suffredini, Peter C. Harpel, Joseph E. Parrillo · New England Journal of Medicine · 1989 · 486 citations

Medicine, Immunology, Pharmacology +14