Alvin Chang

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.

Fletcher B. Taylor, Alvin Chang, CT Esmon et al. · Journal of Clinical Investigation · 1987 · 827 citations · Full text

Microbial Pathogens, Bacteriology, Bacterial Pathogens +18

Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock.

Abla A. Creasey, Alvin Chang, Larry P. Feigen et al. · Journal of Clinical Investigation · 1993 · 549 citations · Full text

Immunology, Inflammation, Thrombosis +21

The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis

Fletcher B. Taylor, Deborah J. Stearns-Kurosawa, Shinichiro Kurosawa et al. · Blood · 2000 · 298 citations

The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons.

Robin A. Pixley, RA De La Cadena, Jimmy D. Page et al. · Journal of Clinical Investigation · 1993 · 277 citations · Full text

Humoral Response, Immunology, Bacteriology +21

Survival of primates in LD100 septic shock following therapy with antibody to tumor necrosis factor (TNF alpha).

L. B. Hinshaw, Patricia Tekamp-Olson, Alvin Chang et al. · PubMed · 1990 · 240 citations

E. Coli, Immunology, Escherichia Coli +16