HA14-1 selectively induces apoptosis in Bcl-2-overexpressing leukemia/lymphoma cells, and enhances cytarabine-induced cell death

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Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

Anthony Letai, Michael C. Bassik, Loren D. Walensky et al. · Cancer Cell · 2002 · 1.6K citations · Full text

Life Sciences, Cancer Biology, Oncology +16

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Life Sciences, Molecular Biology, Oncology +17

bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice

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Medicine, Oncology, Pharmacology +13