Superoxide-Scavenging and Prolyl Endopeptidase Inhibitory Activities of Bangladeshi Indigenous Medicinal Plants

Abstract

The superoxide-scavenging and prolyl endopeptidase (PEP) inhibitory activities of 15 different kinds of Bangladeshi medicinal plants were evaluated. Methanol extraction was performed for the screening tests. Swertia chirata, Emblica officinalis, Zingiber officinale and Myristica malabarica were screened as superoxide-scavenging samples. Similarly, E. officinalis was identified as one of the strongest PEP inhibitory samples. The 50% (O2-)-scavenging and PEP-inhibitory concentrations from E. officinalis methanol extracts were found to be 13.17 and 26.10 microg/ml, respectively.