Concepedia

Antibody conjugation via one and two C-terminal selenocysteines

Xiuling Li, Jiahui Yang, Christoph Rader

Methods · 2013 · 42 citations · 13 references

DOI

Concepts

References

13

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

Jagath R. Junutula, Helga Raab, Suzanna Clark et al. · Nature Biotechnology · 2008 · 1.4K citations

, , +16

Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate

Kevin J. Hamblett, Peter D. Senter, Dana F. Chace et al. · Clinical Cancer Research · 2004 · 1.2K citations

, , +17

Structural characterization of the maytansinoid–monoclonal antibody immunoconjugate, huN901–DM1, by mass spectrometry

Lintao Wang, Godfrey Amphlett, Walter A. Blättler et al. · Protein Science · 2005 · 368 citations · Full text

, , +17

Conserved nucleotide sequences in the open reading frame and 3' untranslated region of selenoprotein P mRNA.

Kristina E. Hill, R. Stephen Lloyd, Raymond F. Burk · Proceedings of the National Academy of Sciences · 1993 · 184 citations

, , +15

The Redox Potential of Selenocystine in Unconstrained Cyclic Peptides

Dörthe Besse, Frank Siedler, Tammo Diercks et al. · Angewandte Chemie International Edition in English · 1997 · 146 citations · Full text

, , +14