Christoph Rader

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

Lizhou Zhang, Cody B. Jackson, Huihui Mou et al. · Nature Communications · 2020 · 1.1K citations · Full text

Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells

Michael Hudecek, Maria Teresa Lupo Stanghellini, Paula L. Kosasih et al. · Clinical Cancer Research · 2013 · 529 citations · Full text

The Nonsignaling Extracellular Spacer Domain of Chimeric Antigen Receptors Is Decisive for <i>In Vivo</i> Antitumor Activity

Michael Hudecek, Daniel Sommermeyer, Paula L. Kosasih et al. · Cancer Immunology Research · 2014 · 510 citations · Full text

Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

Shivani Srivastava, Scott N. Furlan, Carla A. Jaeger-Ruckstuhl et al. · Cancer Cell · 2020 · 316 citations · Full text

Lung Tumors, Tumor Immunology, Cancer Immunosurveillance +11

Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting

Shivani Srivastava, Alexander I. Salter, Denny Liggitt et al. · Cancer Cell · 2019 · 310 citations

Normal Tissues, T-regulatory Cell, Immunology +5