Cystic fibrosis hetero–and homozygosity is associated with inhibition of breast cancer growth

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

Gerene M. Denning, Matthew P. Anderson, Jane F. Amara et al. · Nature · 1992 · 1.2K citations

Life Sciences, Genetics, Molecular Biology +9

An Animal Model for Cystic Fibrosis Made by Gene Targeting

John N. Snouwaert, Kristen K. Brigman, Anne M. Latour et al. · Science · 1992 · 919 citations

Life Sciences, Genetics, Molecular Genetics +15

CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP

Erik M. Schwiebert, Marie E. Egan, Tae-Ho Hwang et al. · Cell · 1995 · 643 citations

Life Sciences, Cell Biology, Molecular Biology +14

The multidrug resistance (mdr1) gene product functions as an ATP channel.

Edward Abraham, A. G. Prat, L.E. Gerweck et al. · Proceedings of the National Academy of Sciences · 1993 · 372 citations

Medicine, Cell Biology, Pharmacology +17

The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel.

I.L. Reisin, A. G. Prat, Edward Abraham et al. · Journal of Biological Chemistry · 1994 · 353 citations · Full text

Life Sciences, Cell Biology, Physiology +17