CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

Natural Sciences, Biophysics, Cell Biology +16

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Identification of the Cystic Fibrosis Gene: Chromosome Walking and Jumping

Johanna M. Rommens, Michael C. Iannuzzi, Bat-Sheva Kerem et al. · Science · 1989 · 3.2K citations

Life Sciences, Genetics, Molecular Genetics +11

Chloride impermeability in cystic fibrosis

Paul Quinton · Nature · 1983 · 758 citations

Natural Sciences, Physiology, Intracellular Transport +13

Expression cloning of an ATP receptor from mouse neuroblastoma cells.

Kevin D. Lustig, Andrew K. Shiau, A J Brake et al. · Proceedings of the National Academy of Sciences · 1993 · 596 citations

Life Sciences, Pharmacology, Physiology +14