Concepedia

Channel Rectification

Channel Rectification is the phenomenon in which a chloride ion channel exhibits asymmetric conductance of ionic current across the membrane in response to changes in transmembrane voltage, permitting greater ion flow in one direction than the other due to voltage-dependent gating or pore block mechanisms.

494

Publications

41.8K

Citations

1.6K

Authors

465

Institutions

Publications per year

2017–2026

52

Parents

Publications

494

Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents.

Michael C. Sanguinetti, Nancy K. Jurkiewicz · The Journal of General Physiology · 1990 · 1.5K citations · Full text

, , +17

Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification

Anatoli N. Lopatin, Elena Makhina, Colin G. Nichols · Nature · 1994 · 854 citations

, , +16

Potassium channels as multi-ion single-file pores.

Bertil Hille, Wolfgang H. Schwarz · The Journal of General Physiology · 1978 · 808 citations · Full text

, , +17

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2

Scott B. Hansen, Xiao Tao, Roderick MacKinnon · Nature · 2011 · 643 citations

, , +14

CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP

Erik M. Schwiebert, Marie E. Egan, Tae-Ho Hwang et al. · Cell · 1995 · 643 citations

, , +14

1–5 of 494

Authors

1.6K

  1. JH
    Jyh‐Ping Hsu

    National Taiwan University, Taiwan

    9 publications · 399 citations

    9

    h-index

  2. YO
    Yasunobu Okada

    National Institute for Physiological Sciences, Japan

    9 publications · 788 citations

    9

    h-index

  3. LJ
    Lei Jiang

    Chinese Academy of Sciences, China

    9 publications · 1K citations

    9

    h-index

  4. CG
    Colin G. Nichols

    Washington University in St. Louis, United States

    9 publications · 1.5K citations

    9

    h-index

  5. ZL
    Zhe Lü

    University of Pennsylvania, United States

    8 publications · 748 citations

    8

    h-index

1–5 of 1.6K

Institutions

465

  1. National Institute for Physiological Sciences

    Okazaki, Japan

    14 h-index

    33 publications

    4K citations

  2. Yale University

    New Haven, United States

    14 h-index

    41 publications

    4.7K citations

  3. Chinese Academy of Sciences

    Beijing, China

    12 h-index

    55 publications

    4.9K citations

  4. University of California, Irvine

    Irvine, United States

    12 h-index

    33 publications

    3.4K citations

  5. Washington University in St. Louis

    St Louis, United States

    12 h-index

    31 publications

    4.9K citations

  6. National Taiwan University

    Taipei, Taiwan

    10 h-index

    29 publications

    1.2K citations

  7. University of Pennsylvania

    Philadelphia, United States

    10 h-index

    21 publications

    1.6K citations

  8. National Taiwan University of Science and Technology

    Taipei, Taiwan

    8 h-index

    11 publications

    582 citations

1–8 of 465

Venues

  1. The Journal of Physiology

    67 publications · 6.2K citations

    40

    h-index

  2. The Journal of General Physiology

    JGP · 41 publications · 5.8K citations

    32

    h-index

  3. American Journal of Physiology-Cell Physiology

    24 publications · 1.5K citations

    19

    h-index

  4. Journal of Biological Chemistry

    JBC · 20 publications · 2.8K citations

    19

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 2.1K citations

    15

    h-index

1–5