Concepedia

Single-channel Recording

Single-Channel Recording is an electrophysiological patch-clamp technique that measures ionic currents flowing through individual ion channel proteins in an isolated membrane patch, thereby resolving their discrete conductance states and kinetic behavior with high temporal and amplitude resolution.

1.7K

Publications

140.3K

Citations

4.8K

Authors

1.1K

Institutions

Publications per year

2017–2026

121

Variants

Single-channel Recordings

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Publications

1.7K

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

, , +16

Single-channel currents recorded from membrane of denervated frog muscle fibres

Erwin Neher, Bert Sakmann · Nature · 1976 · 2.5K citations

, , +14

A TRP Channel that Senses Cold Stimuli and Menthol

Andrea Peier, Aziz Moqrich, Anne C. Hergarden et al. · Cell · 2002 · 2.3K citations · Full text

, , +14

Stretch‐activated single ion channel currents in tissue‐cultured embryonic chick skeletal muscle.

F Guharay, Frederick Sachs · The Journal of Physiology · 1984 · 997 citations · Full text

, , +14

Sodium and calcium channels in bovine chromaffin cells

E M Fenwick, Alain Marty, Erwin Neher · The Journal of Physiology · 1982 · 968 citations

, , +17

1–5 of 1.7K

Authors

4.8K

  1. DC
    David Colquhoun

    University College London, United Kingdom

    22 publications · 1.9K citations

    22

    h-index

  2. FS
    Frederick Sachs

    University at Buffalo, State University of New York, United States

    18 publications · 2.7K citations

    17

    h-index

  3. NF
    Niels Fertig

    Nanion (Germany), Germany

    16 publications · 1.2K citations

    15

    h-index

  4. KL
    Karl L. Magleby

    University of Miami, United States

    13 publications · 1.7K citations

    12

    h-index

  5. OH
    Ole H. Petersen

    University of Liverpool, United Kingdom

    12 publications · 1.2K citations

    12

    h-index

1–5 of 4.8K

Institutions

1.1K

  1. University College London

    London, United Kingdom

    34 h-index

    122 publications

    13.8K citations

  2. Yale University

    New Haven, United States

    27 h-index

    87 publications

    13.1K citations

  3. Max Planck Society

    Munich, Germany

    27 h-index

    67 publications

    30.3K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    25 h-index

    137 publications

    25.8K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    25 h-index

    101 publications

    4K citations

  6. Cornell University

    Ithaca, United States

    20 h-index

    55 publications

    3.5K citations

  7. University of California, Irvine

    Irvine, United States

    19 h-index

    61 publications

    3.9K citations

  8. St George's, University of London

    London, United Kingdom

    19 h-index

    53 publications

    3.8K citations

1–8 of 1.1K

Venues

  1. The Journal of Physiology

    225 publications · 21.1K citations

    77

    h-index

  2. Biophysical Journal

    95 publications · 7.6K citations

    52

    h-index

  3. The Journal of General Physiology

    JGP · 88 publications · 7.4K citations

    48

    h-index

  4. Pflügers Archiv - European Journal of Physiology

    81 publications · 24.1K citations

    40

    h-index

  5. Journal of Neuroscience

    43 publications · 3.5K citations

    35

    h-index

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