Reversible and syntopic interaction between angiotensin receptor antagonists on Chinese hamster ovary cells expressing human angiotensin II type 1 receptors

Nonpeptide angiotensin II receptor antagonists. XI. Pharmacology of EXP3174: an active metabolite of DuP 753, an orally active antihypertensive agent.

Pancras C. Wong, William A. Price, Andrew T. Chiu et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 330 citations

Medicine, Medicinal Chemistry, Pharmacology +9

Pharmacological profile of valsartan: a potent, orally active, nonpeptide antagonist of the angiotensin II AT₁‐receptor subtype

Leoluca Criscione, Marc de Gasparo, Peter Bühlmayer et al. · British Journal of Pharmacology · 1993 · 251 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

QUANTITATIVE STUDIES OF ANTAGONISTS FOR 5‐HYDROXYTRYPTAMINE

J. H. Gaddum, Khan A. Hameed, D. E. Hathway et al. · Quarterly Journal of Experimental Physiology and Cognate Medical Sciences · 1955 · 248 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116).

Yumiko Shibouta, Yasuhiro Inada, M Ojima et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 213 citations

Medicine, Medicinal Chemistry, Pharmacology +13

The renin-angiotensin system

Michel B. Vallotton · Trends in Pharmacological Sciences · 1987 · 200 citations