Concepedia

A chemoenzymatic route to N-acetylglucosamine-1-phosphate analogues: substrate specificity investigations of N-acetylhexosamine 1-kinase

Li Cai, Wanyi Guan, Motomitsu Kitaoka, Jie Shen, Chengfeng Xia, Wenlan Chen, Peng George Wang

Chemical Communications · 2009 · 84 citations · 21 references

DOI

Concepts

Abstract

Reports an efficient chemoenzymatic production of an N-acetylhexosamine 1-phophate analogues library by N-acetylhexosamine 1-kinase (NahK) and describes the respective substrate specificity on this enzyme.

References

21

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David J. Vocadlo, Howard C. Hang, Eun-Ju Kim et al. · Proceedings of the National Academy of Sciences · 2003 · 539 citations · Full text

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Investigating Cellular Metabolism of Synthetic Azidosugars with the Staudinger Ligation

Eliana Saxon, Sarah J. Luchansky, Howard C. Hang et al. · Journal of the American Chemical Society · 2002 · 301 citations

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Synthesis of dibenzyl glycosyl phosphites using dibenzyl N,N-diethylphosphoramidite as phosphitylating reagent: an effective route to glycosyl phosphates, nucleotides, and glycosides

Mui Mui Sim, Hirosato Kondo, Chi Huey Wong · Journal of the American Chemical Society · 1993 · 241 citations

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Identification of<i>N</i>-Acetylhexosamine 1-Kinase in the Complete Lacto-<i>N</i>-Biose I/Galacto-<i>N</i>-Biose Metabolic Pathway in<i>Bifidobacterium longum</i>

Mamoru Nishimoto, Motomitsu Kitaoka · Applied and Environmental Microbiology · 2007 · 196 citations · Full text

, , +11

Molecular Structure of Galactokinase

James B. Thoden, Hazel M. Holden · Journal of Biological Chemistry · 2003 · 74 citations · Full text

, , +13