Concepedia

Thioredoxin Fusions Increase Folding of Single Chain Fv Antibodies in the Cytoplasm of Escherichia coli: Evidence that Chaperone Activity is the Prime Effect of Thioredoxin

Paola Jurado, Vı́ctor de Lorenzo, Luis Ángel Fernández

Journal of Molecular Biology · 2006 · 88 citations · 43 references

DOI

Concepts

References

43

Current protocols in molecular biology

Tom Sargent · Analytical Biochemistry · 1988 · 7.3K citations

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The Role of the Thioredoxin and Glutaredoxin Pathways in Reducing Protein Disulfide Bonds in the Escherichia coliCytoplasm

William A. Prinz, Fredrik Åslund, Arne Holmgren et al. · Journal of Biological Chemistry · 1997 · 672 citations · Full text

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Efficient folding of proteins with multiple disulfide bonds in the <i>Escherichia coli</i> cytoplasm

Paul Bessette, Fredrik Åslund, Jon Beckwith et al. · Proceedings of the National Academy of Sciences · 1999 · 634 citations · Full text

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Disulfide bond formation in the Escherichia coli cytoplasm: an in vivo role reversal for the thioredoxins

The EMBO Journal · 1998 · 428 citations · Full text

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Mutations that Allow Disulfide Bond Formation in the Cytoplasm of <i>Escherichia coli</i>

Alan I. Derman, William A. Prinz, Dominique Belin et al. · Science · 1993 · 427 citations

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