Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease

Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects

Piero Parchi, Armin Giese, Sabina Capellari et al. · Annals of Neurology · 1999 · 1.4K citations

Veterinary Medicine, Genetics, Neurology +17

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

Mark A. Smith, Peggy L.R. Harris, Lawrence M. Sayre et al. · Proceedings of the National Academy of Sciences · 1997 · 1.4K citations

Life Sciences, Neurobiology, Neuroscience +17

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease.

Charles D. Smith, John M. Carney, Pamela Starke‐Reed et al. · Proceedings of the National Academy of Sciences · 1991 · 1.3K citations

Life Sciences, Neurobiology, Neuroscience +17

The cellular prion protein binds copper in vivo

David R. Brown, Kefeng Qin, Jochen Herms et al. · Nature · 1997 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +7

The Advanced Glycation End Product, N∊-(Carboxymethyl)lysine, Is a Product of both Lipid Peroxidation and Glycoxidation Reactions

Min-Xin Fu, Jesús R. Requena, Alicia J. Jenkins et al. · Journal of Biological Chemistry · 1996 · 801 citations · Full text

Life Sciences, Biochemistry, Chemistry +17