IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects

A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

I. Vermes, C. Haanen, H M Steffens-Nakken et al. · Journal of Immunological Methods · 1995 · 5.4K citations · Full text

Life Sciences, Cell Biology, Pathology +13

Participation of p53 protein in the cellular response to DNA damage.

Michael B. Kastan, Onyinye Onyekwere, D Sidransky et al. · PubMed · 1991 · 3.8K citations

Life Sciences, Cell Biology, Molecular Biology +14

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.

Manu Agarwal, Ashok Agarwal, William R. Taylor et al. · Proceedings of the National Academy of Sciences · 1995 · 863 citations

Life Sciences, Cell Biology, Molecular Biology +17

A p53-Dependent Mouse Spindle Checkpoint

Shawn M. Cross, Carissa A. Sanchez, Catherine Morgan et al. · Science · 1995 · 671 citations

Life Sciences, Cell Biology, Genetics +17

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

Alan F. Wahl, Karen Donaldson, Craig Faircnild et al. · Nature Medicine · 1996 · 662 citations

Life Sciences, Cell Biology, Oncology +14