Concepedia

Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid (CB3717), on human lymphoblastoid cells

Robert Jackson, A L Jackman, A H Calvert

Biochemical Pharmacology · 1983 · 111 citations · 29 references

DOI

Concepts

References

29

Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

John F. Morrison · Biochimica et Biophysica Acta (BBA) - Enzymology · 1969 · 814 citations

, , +16

Regulation of Mammalian Deoxyribonucleotide Biosynthesis by Nucleotides as Activators and Inhibitors

E. Colleen Moore, Robert B. Hurlbert · Journal of Biological Chemistry · 1966 · 395 citations · Full text

, , +16

Human lymphoblastoid lines from lymph node and spleen

Jay A. Levy, Martti Virolainen, Vittorio Defendi · Cancer · 1968 · 258 citations · Full text

, , +10

A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in mice

Terence R. Jones, A H Calvert, Ann L. Jackman et al. · European Journal of Cancer (1965) · 1981 · 239 citations

, , +7

An Isotopic Assay for Thymidylate Synthetase<sup>*</sup>

DeWayne Roberts · Biochemistry · 1966 · 212 citations

, , +8