Concepedia

Author

A L Jackman

Institute of Cancer Research

Also Known As

A L Jackman, A.L. Jackman, Ann L. Jackman, Jackman, A.L.

16

Publications

605

Citations

9

H-Index

28

Concepts

All Affiliations

Institute of Cancer Research
AL

About

A L Jackman is an author at Institute of Cancer Research specializing in pharmacology, medicine, and biochemistry.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

6

6

289

2

Biochemistry

4

4

263

3

Natural Sciences

3

3

152

4

Cell Biology

2

2

138

5

Biomolecular Engineering

1

1

14

A L Jackman

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9

Publications

589

Citations

9

H-Index

YearCitations

Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.

G R Westerhof, Jan H. Schornagel, Ietje Kathmann,

Molecular Pharmacology

1995

203

Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid (CB3717), on human lymphoblastoid cells

Robert Jackson, A L Jackman, A H Calvert

Biochemical Pharmacology

1983

111

Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems.

G R Westerhof, Gerrit Jansen, Nancy van Emmerik,

PubMed

1991

75

Phase I trial of ZD1694, a new folate-based thymidylate synthase inhibitor, in patients with solid tumors.

Stephen Clarke, Janet Hanwell, M. de Boer,

Journal of Clinical Oncology

1996

74

Formation and retention and biological activity of N10-propargyl-5, 8-dideazafolic acid (CB3717) polyglutamates in L1210 cells in vitro

Ewa Sikora, A L Jackman, David R. Newell,

Biochemical Pharmacology

1988

63

Quinazoline antifolate thymidylate synthase inhibitors: 2'-Fluoro-N10-propargyl-5,8,-dideazafolic acid and derivatives with modifications in the C-2 position

A L Jackman, Peter R. Marsham, Timothy J. Thornton,

Journal of Medicinal Chemistry

1990

23

Nonpolyglutamatable Antifolates as Inhibitors of Thymidylate Synthase (TS) and Potential Antitumour Agents

Vassilios Bavetsias, A L Jackman

Current Medicinal Chemistry

1998

14

A novel, orally administered nucleoside analogue, OGT 719, inhibits the liver invasive growth of a human colorectal tumor, C170HM2.

Christian Rohlff, S A Watson, Teresa Morris,

PubMed

1999

13

Estimation of the In Vitro and In Vivo Inhibitory Effects of Antifolates upon Thymidylate Synthase (TS) in Whole Cells

Geoffrey A. Taylor, A L Jackman, Kathryn Balmanno,

Advances in experimental medicine and biology

1989

13

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