Ietje Kathmann

Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.

G R Westerhof, Jan H. Schornagel, Ietje Kathmann et al. · Molecular Pharmacology · 1995 · 203 citations

A Structurally Altered Human Reduced Folate Carrier with Increased Folic Acid Transport Mediates a Novel Mechanism of Antifolate Resistance

Gerrit Jansen, Robert Mauritz, Stavit Drori et al. · Journal of Biological Chemistry · 1998 · 163 citations · Full text

Hematological Malignancy, Novel Mechanism, Cem/mtx-low Folate +14

The Human Multidrug Resistance Protein MRP5 Transports Folates and Can Mediate Cellular Resistance against Antifolates

Peter R. Wielinga, Jan Hendrik Hooijberg, Sjöfn Gunnarsdottir et al. · Cancer Research · 2005 · 138 citations · Full text

Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates.

Gerrit Jansen, G R Westerhof, M J Jarmuszewski et al. · Journal of Biological Chemistry · 1990 · 101 citations · Full text

Chemoprevention Strategy, Mixed-phenotype Acute Leukemia, Cell Culture Medium +16

Loss of Multidrug Resistance Protein 1 Expression and Folate Efflux Activity Results in a Highly Concentrative Folate Transport in Human Leukemia Cells

Yehuda G. Assaraf, Lilah Rothem, Jan Hendrik Hooijberg et al. · Journal of Biological Chemistry · 2003 · 77 citations · Full text