G R Westerhof

Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.

G R Westerhof, Jan H. Schornagel, Ietje Kathmann et al. · Molecular Pharmacology · 1995 · 205 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates.

Gerrit Jansen, G R Westerhof, M J Jarmuszewski et al. · Journal of Biological Chemistry · 1990 · 101 citations · Full text

Medicine, Cancer Biology, Pharmacology +16

Comparison of different busulfan analogues for depletion of hematopoietic stem cells and promotion of donor-type chimerism in murine bone marrow transplant recipients.

G R Westerhof, Rob E. Ploemacher, A Boudewijn et al. · PubMed · 2000 · 92 citations · Full text

Medicine, Pharmacology, Cell Therapy +16

Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems.

G R Westerhof, Gerrit Jansen, Nancy van Emmerik et al. · PubMed · 1991 · 75 citations

Medicine, Biochemistry, Pharmacology +12

Expression of a folate binding protein in L1210 cells grown in low folate medium.

Gerrit Jansen, Ietje Kathmann, B. Rademaker et al. · PubMed · 1989 · 73 citations

Life Sciences, Biochemistry, Cancer Biology +10