G R Westerhof

Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.

G R Westerhof, Jan H. Schornagel, Ietje Kathmann et al. · Molecular Pharmacology · 1995 · 203 citations

Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates.

Gerrit Jansen, G R Westerhof, M J Jarmuszewski et al. · Journal of Biological Chemistry · 1990 · 101 citations · Full text

Chemoprevention Strategy, Mixed-phenotype Acute Leukemia, Cell Culture Medium +16

Comparison of different busulfan analogues for depletion of hematopoietic stem cells and promotion of donor-type chimerism in murine bone marrow transplant recipients.

G R Westerhof, Rob E. Ploemacher, A Boudewijn et al. · PubMed · 2000 · 92 citations

Different Busulfan Analogues, Cell Therapy, Immunology +19

Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems.

G R Westerhof, Gerrit Jansen, Nancy van Emmerik et al. · PubMed · 1991 · 75 citations

Antifolate Compounds, Cancer Biology, Cellular Physiology +17

Expression of a folate binding protein in L1210 cells grown in low folate medium.

Gerrit Jansen, Ietje Kathmann, B. Rademaker et al. · PubMed · 1989 · 73 citations

Biochemistry, Medicine, Natural Sciences +9