Concepedia

Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2

Jingbo Pi, Bhalchandra A. Diwan, Yang Sun, Jie Liu, Wei Qu, Yu‐Ying He, Miroslav Stýblo, Michael P. Waalkes

Free Radical Biology and Medicine · 2008 · 181 citations · 41 references

DOI

Concepts

References

41

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

Petra Boukamp, R T Petrussevska, Dirk Breitkreutz et al. · The Journal of Cell Biology · 1988 · 4.2K citations · Full text

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in <i>nrf2</i> transcription factor-deficient mice

Minerva Ramos‐Gómez, Mi-Kyoung Kwak, Patrick M. Dolan et al. · Proceedings of the National Academy of Sciences · 2001 · 1.1K citations · Full text

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Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer

Anju Singh, Vikas Misra, Rajesh K. Thimmulappa et al. · PLoS Medicine · 2006 · 1K citations · Full text

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Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

Nobunao Wakabayashi, Ken Itoh, Junko Wakabayashi et al. · Nature Genetics · 2003 · 888 citations

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An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen

Xiao-Dong Han, Yuet Wai Kan · Proceedings of the National Academy of Sciences · 2001 · 763 citations · Full text

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