Determination of stavudine, a new antiretroviral agent, in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection

The Efficacy of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex

Margaret A. Fischl, Douglas D. Richman, Michael H. Grieco et al. · New England Journal of Medicine · 1987 · 3K citations

Life Sciences, Immunology, Pharmacology +16

Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro

Masanori Baba, Rudi Pauwels, Piet Herdewijn et al. · Biochemical and Biophysical Research Communications · 1987 · 344 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Potent and selective in vitro activity of 3' -deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus

Tai‐Shun Lin, Raymond F. Schinazi, William H. Prusoff · Biochemical Pharmacology · 1987 · 261 citations

Medicine, Medicinal Chemistry, Pharmacology +7

The anti-HTLV-III (anti-HIV) and cytotoxic activity of 2',3'-didehydro-2',3'-dideoxyribonucleosides: a comparison with their parental 2',3'-dideoxyribonucleosides.

Jan Balzarini, Gil-Jong Kang, Maha Dalal et al. · Molecular Pharmacology · 1987 · 234 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus

Yosuke Hamamoto, Hiroshi Nakashima, T Matsui et al. · Antimicrobial Agents and Chemotherapy · 1987 · 212 citations · Full text

Medicine, Infectious Diseases, Pharmacology +16