Concepedia

Volume to dissolve applied dose (VDAD) and apparent dissolution rate (ADR): Tools to predict in vivo bioavailability from orally applied drug suspensions

Uwe Muenster, Christian Pelzetter, Thomas Backensfeld, Andreas Ohm, Thomas Kuhlmann, Hartwig Mueller, Klemens Lustig, Jörg Keldenich, Susanne Greschat, Andreas H. Göller,

European Journal of Pharmaceutics and Biopharmaceutics · 2011 · 15 citations · 21 references

DOI

Concepts

References

21

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

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Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

Peter Ertl, Bernhard Rohde, Paul M. Selzer · Journal of Medicinal Chemistry · 2000 · 3K citations

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Epik: a software program for pK a prediction and protonation state generation for drug-like molecules

John C. Shelley, Anuradha Cholleti, Leah L. Frye et al. · Journal of Computer-Aided Molecular Design · 2007 · 2.1K citations

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In Vitro Permeability Across Caco-2 Cells (Colonic) Can Predict In Vivo (Small Intestinal) Absorption in Man—Fact or Myth

Shiyin Yee · Pharmaceutical Research · 1997 · 1K citations

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Molecular Properties of WHO Essential Drugs and Provisional Biopharmaceutical Classification

Nehal A. Kasim, Marc Whitehouse, Chandrasekharan Ramachandran et al. · Molecular Pharmaceutics · 2003 · 844 citations

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