In Vitro and In Vivo P-Glycoprotein Transport Characteristics of Rivaroxaban

Mark Jean Gnoth, Ulf Buetehorn, Uwe Muenster, +2

Journal of Pharmacology and Experimental Therapeutics

Validation of Dissolution Testing with Biorelevant Media: An OrBiTo Study

James Mann, Jennifer Dressman, Karin M. Rosenblatt, +17

Molecular Pharmaceutics

Pharmaceutical ScienceEngineeringGastroenterologyBiomedical EngineeringOrbito Study +16

Nanocrystals embedded in chitosan-based respirable swellable microparticles as dry powder for sustained pulmonary drug delivery

Rui Ni, Jing Zhao, Qiaoyu Liu, +3

European Journal of Pharmaceutical Sciences

NanoparticlesNanomedicineEngineeringNanomaterialsPharmaceutical Nanotechnology +5

Exploring polyvinylpyrrolidone in the engineering of large porous PLGA microparticles via single emulsion method with tunable sustained release in the lung: In vitro and in vivo characterization

Rui Ni, Uwe Muenster, Jing Zhao, +4

Journal of Controlled Release

Single Emulsion MethodTunable Sustained ReleaseEngineeringPolymer ScienceMicro-encapsulation +5

Characterization of Substrates and Inhibitors for the In Vitro Assessment of Bcrp Mediated Drug–Drug Interactions

Uwe Muenster, Birgit Grieshop, Karsten Ickenroth, +1

Pharmaceutical Research

Molecular PharmacologyDrug TargetBiochemistryDrug ResistanceMedicine +7

Interlaboratory Validation of Small-Scale Solubility and Dissolution Measurements of Poorly Water-Soluble Drugs

Sara Andersson, Caroline Alvebratt, Jan Bevernage, +14

Journal of Pharmaceutical Sciences

MedicineDrug PuritySmall-scale SolubilityAnalytical ChemistryPoorly Water-soluble Drugs +7

IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

Alison Margolskee, Adam S. Darwich, Xavier Pépin, +43

European Journal of Pharmaceutical Sciences

Pharmacokinetic ModelingBiochemistryMedicineRational Drug DesignAnalytical Chemistry +6

Sustained therapeutic efficacy of budesonide-loaded chitosan swellable microparticles after lung delivery: Influence of in vitro release, treatment interval and dose

Lan Zhang, Linglong Yang, Xiaofei Zhang, +9

Journal of Controlled Release

NanomedicineLung DeliveryEngineeringLung DepositionTreatment Interval +5

Can dosage form-dependent food effects be predicted using biorelevant dissolution tests? Case example extended release nifedipine

Cord J. Andreas, Irena Tomaszewska, Uwe Muenster, +3

European Journal of Pharmaceutics and Biopharmaceutics

NutritionBiorelevant Dissolution TestsDietary ExposureBioequivalenceMedicine +7

Application of a Refined Developability Classification System

Julian Rosenberger, James Butler, Uwe Muenster, +1

Journal of Pharmaceutical Sciences

Software MaintenanceEngineeringSoftware Development ProcessProgram AnalysisSoftware Testing +7