Concepedia

Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1

Marcin Kortylewski, Peter C. Heinrich, Andrzej Maćkiewicz, Ute Schniertshauer, Ursula Klingmüller, Koichi Nakajima, Toshio Hirano, Friedemann Horn, Iris Behrmann

Oncogene · 1999 · 139 citations · 53 references

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References

53

Stat3: a STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6

Zhong Zhong, Zilong Wen, James Darnell · Science · 1994 · 2.1K citations

, , +14

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

Hitoshi Niwa, Tom Burdon, Ian Chambers et al. · Genes & Development · 1998 · 1.5K citations · Full text

, , +15

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

Tetsuya Taga, Masahiko Hibi, Yuuichi Hirata et al. · Cell · 1989 · 1.4K citations

, , +14

Choice of STATs and Other Substrates Specified by Modular Tyrosine-Based Motifs in Cytokine Receptors

Neil Stahl, Thomas J. Farruggella, Teri G. Boulton et al. · Science · 1995 · 992 citations

, , +17

The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor

David P. Gearing, Michael R. Comeau, Della Friend et al. · Science · 1992 · 897 citations

, , +13