Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

Hitoshi Niwa, Tom Burdon, Ian Chambers, +1

Genes & Development

Regenerative MedicineLineage PlasticityInduced Pluripotent Stem CellDevelopmental BiologyCell Regulation +12

Suppression of SHP-2 and ERK Signalling Promotes Self-Renewal of Mouse Embryonic Stem Cells

Tom Burdon, Craig Stracey, Ian Chambers, +2

Developmental Biology

Induced Pluripotent Stem CellSignal TransductionDevelopmental BiologyMedicineStem Cell Research +4

Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

Michael J. Devine, Mina Ryten, Petr Vodička, +12

Nature Communications

Oct-4 Knockdown Induces Similar Patterns of Endoderm and Trophoblast Differentiation Markers in Human and Mouse Embryonic Stem Cells

David C. Hay, Linda Sutherland, J. F. Clark, +1

Stem Cells

Analysis of Oct4-Dependent Transcriptional Networks Regulating Self-Renewal and Pluripotency in Human Embryonic Stem Cells

Yasmin Babaie, Ralf Herwig, Boris Greber, +6

Stem Cells

An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment

Magnus Lynch, Andrew J. H. Smith, Marco De Gobbi, +12

The EMBO Journal

BiologyChromatinKey RoleMedicineGenetics +9

Expression of a whey acidic protein transgene during mammary development. Evidence for different mechanisms of regulation during pregnancy and lactation.

Tom Burdon, Lakshmanan Sankaran, R.J. Wall, +2

Journal of Biological Chemistry

Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the <i>Csf1r</i> Locus

Clare Pridans, Anna Raper, Gemma M. Davis, +23

The Journal of Immunology

Paracrine Induction of Stem Cell Renewal by LIF-Deficient Cells: A New ES Cell Regulatory Pathway

Christian Dani, Ian Chambers, Stephen R. Johnstone, +8

Developmental Biology

Developmental BiologyCell RegulationCell SpecializationStem Cell RenewalMedicine +8

Over-expression of an endogenous milk protein gene in transgenic mice is associated with impaired mammary alveolar development and a milchlos phenotype

Tom Burdon, R.J. Wall, Avi Shamay, +2

Mechanisms of Development

Developmental BiologyProtein ExpressionLactationMedicineGenetics +11